Diabetes supplements


Today we are talking about the benefits of berberine and berberine side effects in detail. Recently, berberine supplements have come under the spotlight in .


Today we are talking about the benefits of berberine and berberine side effects in detail. Recently, berberine supplements have come under the spotlight in the Western world because of their ability to regulate blood sugar levels as one of the best diabetic supplements to activate the longevity pathway AMPK (adenosine monophosphate-activated protein kinase), which is the metabolism’s “master switch,” which helps with weight loss and even fight cancers. Because of all these advantages, berberine is a beneficial supplement for delaying aging, and diabetes and increasing longevity. So in this blog, we will talk about berberine benefits and berberine side effects.

berberine supplement
Berberine C20H18NO4, herbal alkaloid molecule. Structural chemical formula on the dark blue background. Illustration

The positive benefits of berberine in diabetes and obesity treatment are partly due to stimulation of the AMP-activated protein kinase (AMPK) signaling pathway.  It is a mouthful, isn’t it? AMPK, an enzyme found in cells, is a metabolic master switch that helps control cell energy. It’s one of the pathways we want to trigger With SugarMD Super Berberine, a blend of dihdyroberberine and Ceylon cinnamon. If you remember, dihydro-berberine is five times more absorbable than berberine and has fewer gastrointestinal adverse effects.

Berberine has been the subject of many investigations. Those studies have revealed that it can control blood sugar levels, help lose weight and improve cholesterol in several ways.

Berberine Benefits Include But Not Limited To:

  • Reduces insulin resistance, resulting in increased responsiveness to the hormone insulin.
  • Berberine works to lower blood sugar levels by activating an enzyme called AMPK, which then causes muscles, the liver, and adipose tissue to take in more glucose.
  • Boosts the rate at which glucose is metabolized within the cells (glycolysis).
  • It contributes to the gut’s ability to slowly break down carbohydrates, which helps avoid blood sugar swings.
  • It contributes to regulating the microbiome in the gut, which is vital for the function of many of our systems.
  • Reduces the amount of sugar that is produced by the liver.


Participants in research with type 2 diabetes and dyslipidemia (an abnormal quantity of fat in the blood) who were given 1 gram of berberine per day reduced their fasting blood sugar from diabetic to normal levels according to the findings of the study, including 116 patients. The study’s findings led the researchers to conclude that berberine is an effective and safe treatment for type 2 diabetes. It is important to remember that the recommended dosage of dihydroberberine, which is just 200 mg, is equivalent to 1000 mg of conventional berberine.

How Does Berberine Work?

When cells need energy, they turn to ATP (adenosine triphosphate). ATP is often referred to as the cell powerhouse because it supplies cells with the energy they need to function. If ATP levels are low, your cells won’t be able to function correctly. Fortunately, berberine can help to replenish ATP supplies by activating AMPK (AMP-activated protein kinase). AMPK is a signaling pathway that modulates the production of ATP. In other words, it helps to ramp up fatty acid oxidation, which enhances your energy levels and helps you burn fat.

Even more impressive is that berberine is just as effective as metformin at managing blood sugar levels. Metformin is a well-known prescription medication for type 2 diabetes and high blood sugar levels. But unlike metformin, berberine doesn’t come with any adverse effects. That’s why berberine is such a popular supplement for people looking to improve their energy levels and manage their blood sugar levels.


Super berberine
SUGARMD Super berberine


Although berberine and metformin are distinct structurally, they have several benefits in common. However, many individuals, for various reasons, are wary of metformin. Berberine is a type of supplement that is helpful in the management of diabetes. It is structurally similar to metformin, and like metformin, it helps to increase insulin sensitivity and lower blood sugar levels. However, there are some important differences between the two supplements. For one, berberine is derived from a plant, while metformin is a synthetic drug.

Additionally, berberine has been shown to have other health benefits beyond blood sugar control, including improving cholesterol levels and reducing inflammation. Finally, berberine is not associated with severe side effects, unlike metformin. Overall, berberine is a safe and effective option for those looking to manage their diabetes. Click on this link to learn more about metformin side effects.

Both berberine and metformin are beneficial in helping to regulate blood sugar levels, perhaps manage weight, and lower cholesterol levels.

On the other hand, their adverse effects are quite different. And this is one of the numerous reasons berberine may be a better alternative for some than metformin.

Another advantage is that you can purchase it without a doctor’s prescription.

Can Berberine Help with Weight Loss and PCOS?

Relief of PCOS Symptoms

PCOS, also known as polycystic ovary syndrome, can result in issues like excessive cholesterol, insulin resistance, and difficulty reducing weight. According to specific research, berberine improved insulin response decreased waist-to-hip ratio, and controlled cholesterol in women with PCOS.

Weight loss

Although berberine is not a miracle weight-reduction drug, it might aid in weight loss in those with a body mass index (BMI) of 30 or above. According to two studies, taking a berberine supplement for three months causes noticeable weight loss. This could be as a result of berberine’s role in the regulation of insulin and other hormones that control your fat cells.

Berberine Adverse Effects

Berberine is a plant extract that is safe to take orally. While berberine is generally safe, it can cause some side effects. The most common side effect is gastrointestinal distress, including nausea, vomiting, and diarrhea. Berberine can also cause lightheadedness, drowsiness, and dry mouth. In rare cases, berberine can cause more severe side effects, such as liver damage and low blood pressure.

To help combat potential side effects, we have used dihydroberberine in SugarMD Super Berberine, a modified form of berberine to allow better absorption, along with 20 times concentrated Ceylon Cinnamon. They are still 100 percent organic and natural.

Who should not take Berberine Due to Unknown Effects?

Pregnant and breastfeeding mothers should avoid berberine because it can cross the placenta and harm the unborn child or pass through breast milk to the baby during breastfeeding.

Also, if you already have a low blood pressure line 100/50 or lower, taking berberine may cause it to drop even lower, so use it with caution and under the supervision of your doctor.

Check out our SugarMD super berberine product at sugarmds.com and see if it will fit your needs! See you in the following video.

To Summarize:

Berberine supplements have recently gained popularity in the West due to their ability to regulate blood sugar levels as one of the best diabetic supplements to activate the longevity pathway AMPK (adenosine monophosphate-activated protein kinase), which aids in weight loss and cancer prevention. Berberine helps with aging, diabetes, and overall longevity. This blog discusses the benefits and drawbacks of berberine.

Berberine promotes the AMPK signaling system, which aids in treating diabetes and obesity.

Berberine advantages include:

  • Insulin resistance is reduced, and insulin sensitivity is increased.
  • Berberine lowers blood sugar by activating AMPK, which causes more glucose to be absorbed by the muscles, liver, and fat.
  • Boosts cell glucose metabolism (glycolysis).
  • It aids the intestines in slowly breaking down carbohydrates, preventing blood sugar spikes.
  • It regulates the gut microbiota, which is essential for many systems.
  • Lowers liver’s glucose output.

Berberine and metformin have similar benefits despite their different structures. Metformin is unpopular for a variety of reasons. Berberine aids in diabetes management. It, like metformin, improves insulin sensitivity and lowers blood sugar levels. The two supplements are not the same. Berberine, unlike metformin, comes from a plant.

Berberine improves cholesterol and reduces inflammation in addition to controlling blood sugar. Berberine, unlike metformin, has few side effects. Berberine is a diabetic treatment that is both safe and effective.

Berberine is safe to take orally. Berberine, while generally safe, can have adverse effects. Nausea, vomiting, and diarrhea are common side effects. Lightheadedness, sleepiness, and dry mouth are all possible side effects. Berberine rarely causes liver damage or low blood pressure.

SUGARMD Super Berberine:

SugarMD Super Berberine contains dihydroberberine, a modified version of berberine for improved absorption, and Ceylon Cinnamon which is 20 times concentrated on reducing side effects. Natural and organic products.

Berberine can cross the placenta and harm the baby during pregnancy and breastfeeding.

Berberine may lower your blood pressure more if it is 100/50 or lower, so use caution and under a doctor’s supervision.


About the author:

Who is Dr. Ergin? Dr. Ahmet Ergin is an endocrinologist interested in and passionate about diabetes care. Dr. Ergin earned his medical degree with honors at Marmara University School of Medicine in Istanbul, Turkey. Then, he completed his internal medicine residency and endocrinology fellowship at Cleveland Clinic in Cleveland, Ohio. He is a board-certified Internal Medicine and Endocrinology, diabetes, and metabolism physician. He is also a certified diabetes education specialist.

Disclaimer: Any information on diseases and treatments on this website is for general guidance only and must never be a substitute for the advice your doctor or other qualified healthcare professional provides. Always seek the advice of your physician or other qualified health care professional with questions you may have regarding your medical condition.