Benfotiamine can protect and maintain endothelial (vascular wall) health that may be damaged by high blood sugar. Alpha-lipoic acid boosts nerve anti-oxidant defense against neuropathy. B12 helps protect nerve myelin sheath. Without it, nerves die, causing diseases like neuropathy. A B12 shortage is common in people taking metformin and this can cause neurological and cognitive impairment. Vitamin B6 helps protect nerve endings.
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